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OtherA laboratory abnormality associated with triamterene is spurious elevation of lactate dehydrogenase concentrations. Triamterene is a member of the drug class potassium-sparing diuretics. , spironolactone, triamterene, or amiloride), since the simultaneous administration of these agents can produce severe hyperkalemia. A case of cholestatic jaundice and centrolobular necrosis of the liver has been associated with triamterene (probably related to hypersensitivity to the drug). Triamterene interferes with the fluorescent measurement of quinidine, resulting in erroneous values of the serum quinidine concentration.
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