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However, allopurinol did not cause birth defects or other problems in rats or rabbits given doses up to 20 times the amount usually given to humans. A reaction with another antigout drug, allopurinol, may cause a rash. The addition of allopurinol may help to protect the renal tubules from long-term damage due to uric acid crystallization. Allopurinol will help prevent gout attacks only as long as you continue to take it. It is not known whether this potentiation of ampicillin rashes is due to allopurinol or the hyperuricemia present in these patients.
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