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Brand name: levonorgestrel
Generic name: plan-b, Levonorgestrel, Levonelle, NorLevo, Postinor, birth control
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Following administration of 200 mg of Fluconazole, the mean percentage increase of AUC for levonorgestrel compared to placebo was 25% (range: -12 to 82%) and the mean percentage increase for ethinyl estradiol compared to placebo was 38% (range: -11 to 101%). Repeated daily doses of the oral contraceptive (OC) given 30 minutes after Byetta administration decreased the Cmax of ethinyl estradiol and levonorgestrel by 45% and 27%, respectively and delayed the Tmax of ethinyl estradiol and levonorgestrel by 3. Administration of repeated daily doses of the OC one hour prior to Byetta administration decreased the mean Cmax of ethinyl estradiol by 15% but the mean Cmax of levonorgestrel was not significantly changed as compared to when the OC was given alone. Using levonorgestrel (a progestin) with estradiol can lower the risk of developing this condition. Be sure to also have regular annual pelvic exams and Pap smears while you are using the levonorgestrel intrauterine system.
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